{"id":370794,"date":"2026-03-19T10:45:53","date_gmt":"2026-03-19T09:45:53","guid":{"rendered":"https:\/\/zakrasnejsivimperk.cz\/?p=370794"},"modified":"2026-03-19T10:46:26","modified_gmt":"2026-03-19T09:46:26","slug":"ceska-republika-strevni-mikrobiom-miluje-vlakninu-potvrdily-to-i-tasemnice","status":"publish","type":"post","link":"https:\/\/zakrasnejsivimperk.cz\/?p=370794","title":{"rendered":"\u010cESK\u00c1 REPUBLIKA: St\u0159evn\u00ed mikrobiom miluje vl\u00e1kninu. Potvrdily to tak\u00e9 tasemnice"},"content":{"rendered":"
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Na sn\u00edmku: tasemnice krys\u00ed Hymenolepis diminuta je v dobr\u00e9 kondici, pokud je ve strav\u011b velk\u00fd pod\u00edl vl\u00e1kniny (A). P\u0159i diet\u011b chud\u00e9 na vl\u00e1kninu z\u016fst\u00e1v\u00e1 tasemnice n\u011bkolikan\u00e1sobn\u011b men\u0161\u00ed a p\u0159ech\u00e1z\u00ed do \u00fasporn\u00e9ho re\u017eimu p\u0159ipom\u00ednaj\u00edc\u00edho hibernaci (B). Foto: BC AV \u010cR<\/figcaption><\/figure>\n

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St\u0159evn\u00ed \u010dervi mohou tlumit z\u00e1n\u011bt v lidsk\u00e9m t\u011ble \u2013 ale jen pokud maj\u00ed dostatek vl\u00e1kniny. Bez n\u00ed se jejich organismus p\u0159epne do jak\u00e9hosi hiberna\u010dn\u00edho re\u017eimu a ochrann\u00fd efekt miz\u00ed. Ukazuje to nov\u00e1 studie parazitolog\u016f z Biologick\u00e9ho centra Akademie v\u011bd \u010cR publikovan\u00e1 v presti\u017en\u00edm \u010dasopise Nature Communications.<\/h6>\n

\"\"St\u0159evn\u00ed parazit\u00e9 byli po v\u011bt\u0161inu evolu\u010dn\u00ed historie b\u011b\u017enou sou\u010d\u00e1st\u00ed lidsk\u00e9ho tr\u00e1vic\u00edho traktu. V pr\u016fmyslov\u00fdch zem\u00edch v posledn\u00edch desetilet\u00edch t\u00e9m\u011b\u0159 vymizeli, co\u017e se obvykle vysv\u011btluje zlep\u0161enou hygienou a modern\u00ed medic\u00ednou. Sou\u010dasn\u011b ale v modern\u00ed populaci v\u00fdrazn\u011b p\u0159ib\u00fdv\u00e1 autoimunitn\u00edch a z\u00e1n\u011btliv\u00fdch onemocn\u011bn\u00ed st\u0159ev. Proto se p\u0159ibli\u017en\u011b p\u0159ed dvaceti lety v\u011bdci za\u010dali zab\u00fdvat my\u0161lenkou vyu\u017e\u00edt n\u011bkter\u00e9 st\u0159evn\u00ed \u010dervy jako terapeutick\u00fd n\u00e1stroj (tzv. helmintoterapie).<\/p>\n

\u201eV\u00fdsledky helmintoterapie jsou ale zat\u00edm nekonzistentn\u00ed \u2013 n\u011bkdy \u010dervi z\u00e1n\u011bt tlum\u00ed a n\u011bkdy ne. Proto jsme se zam\u011b\u0159ili na faktory, kter\u00e9 mohou jejich \u00fa\u010dinek ve st\u0159ev\u011b ovliv\u0148ovat,\u201c<\/em> \u0159\u00edk\u00e1 Kate\u0159ina Jirk\u016f z Parazitologick\u00e9ho \u00fastavu Biologick\u00e9ho centra AV \u010cR. Uk\u00e1zalo se, \u017ee kl\u00ed\u010dovou roli hraje slo\u017een\u00ed stravy, p\u0159edev\u0161\u00edm mno\u017estv\u00ed vl\u00e1kniny.<\/p>\n

V\u011bdci sledovali, jak se st\u0159evn\u00ed parazit chov\u00e1 p\u0159i r\u016fzn\u00e9m mno\u017estv\u00ed vl\u00e1kniny ve strav\u011b hostitele. Jako modelov\u00fd organismus pou\u017eili tasemnici krys\u00ed Hymenolepis diminuta, kter\u00e1 se b\u011b\u017en\u011b vyu\u017e\u00edv\u00e1 ve v\u00fdzkumu interakc\u00ed mezi parazity, st\u0159evn\u00edmi mikroorganismy a imunitn\u00edm syst\u00e9mem, hostiteli ne\u0161kod\u00ed, naopak dok\u00e1\u017ee tlumit z\u00e1n\u011bt.<\/p>\n

\u201eZjistili jsme, \u017ee kdy\u017e je ve strav\u011b velk\u00fd pod\u00edl struktur\u00e1ln\u00ed vl\u00e1kniny, tasemnice je nejen ve v\u00fdborn\u00e9 kondici, ale je schopna vyvol\u00e1vat i protiz\u00e1n\u011btlivou reakci v organismu hostitele. Kdy\u017e vl\u00e1knina chyb\u00ed, tasemnice p\u0159ech\u00e1z\u00ed do \u00fasporn\u00e9ho re\u017eimu p\u0159ipom\u00ednaj\u00edc\u00edho hibernaci u savc\u016f a jej\u00ed protiz\u00e1n\u011btliv\u00fd \u00fa\u010dinek miz\u00ed,\u201c<\/em> uv\u00e1d\u00ed Kate\u0159ina Jirk\u016f. P\u0159i diet\u011b chud\u00e9 na vl\u00e1kninu z\u016fst\u00e1valy tasemnice n\u011bkolikan\u00e1sobn\u011b men\u0161\u00ed, nedosahovaly pohlavn\u00ed zralosti a neprodukovaly vaj\u00ed\u010dka. Genetick\u00e9 anal\u00fdzy nav\u00edc uk\u00e1zaly, \u017ee u t\u011bchto \u010derv\u016f doch\u00e1z\u00ed k rozs\u00e1hl\u00fdm zm\u011bn\u00e1m v aktivit\u011b gen\u016f spojen\u00fdch s v\u00fdvojem, metabolismem a reprodukc\u00ed.<\/p>\n

Strava m\u011bn\u00ed cel\u00fd st\u0159evn\u00ed ekosyst\u00e9m<\/h6>\n

Zm\u011bny ve strav\u011b v\u00fdrazn\u011b ovliv\u0148ovaly cel\u00fd st\u0159evn\u00ed mikrobiom hostitele. Strava bohat\u00e1 na vl\u00e1kninu podporovala bakterie spojen\u00e9 se zdrav\u00fdm st\u0159evn\u00edm prost\u0159ed\u00edm. Naproti tomu z\u00e1padn\u00ed dieta vedla k ni\u017e\u0161\u00ed pestrosti mikrob\u016f a k roz\u0161\u00ed\u0159en\u00ed bakteri\u00ed spojovan\u00fdch se st\u0159evn\u00ed nerovnov\u00e1hou. Tyto rozd\u00edly se prom\u00edtly i do imunitn\u00ed reakce hostitele.<\/p>\n

Podle odborn\u00edk\u016f tak v\u00fdsledky studie znovu ukazuj\u00ed, jak z\u00e1sadn\u00ed roli hraje slo\u017een\u00ed stravy pro fungov\u00e1n\u00ed cel\u00e9ho st\u0159evn\u00edho ekosyst\u00e9mu. Zdravotnick\u00e9 organizace doporu\u010duj\u00ed dosp\u011bl\u00fdm p\u0159ij\u00edmat p\u0159ibli\u017en\u011b 25 a\u017e 30 gram\u016f vl\u00e1kniny denn\u011b, skute\u010dn\u00e1 spot\u0159eba v z\u00e1padn\u00edch zem\u00edch je v\u0161ak \u010dasto je\u0161t\u011b ni\u017e\u0161\u00ed. Pro srovn\u00e1n\u00ed \u2013 u n\u011bkter\u00fdch tradi\u010dn\u00edch populac\u00ed se odhaduje p\u0159\u00edjem vl\u00e1kniny a\u017e kolem 80\u2013120 gram\u016f denn\u011b.<\/p>\n

Nedostatek vl\u00e1kniny p\u0159itom ochuzuje st\u0159evn\u00ed mikrobiom, kter\u00fd m\u00e1 podle \u0159ady studi\u00ed vliv nejen na zdrav\u00ed tr\u00e1vic\u00edho traktu, ale i na fungov\u00e1n\u00ed imunitn\u00edho syst\u00e9mu, mozku i psychiky. Nerovnov\u00e1ha st\u0159evn\u00edch mikroorganism\u016f je dnes spojov\u00e1na nap\u0159\u00edklad se zv\u00fd\u0161en\u00fdm rizikem alergi\u00ed, depres\u00ed, \u00fazkost\u00ed \u010di neurodegenerativn\u00edch onemocn\u011bn\u00ed, v\u010detn\u011b Alzheimerovy choroby.<\/p>\n

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Text a foto: (tz-av\u010dr)<\/strong><\/p>\n

\n

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  St\u0159evn\u00ed <\/p>\n","protected":false},"author":2,"featured_media":370795,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"footnotes":""},"categories":[19,174],"tags":[],"jetpack_featured_media_url":"https:\/\/zakrasnejsivimperk.cz\/wp-content\/uploads\/2026\/03\/19\/tasemnice.jpg","_links":{"self":[{"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=\/wp\/v2\/posts\/370794"}],"collection":[{"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=370794"}],"version-history":[{"count":2,"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=\/wp\/v2\/posts\/370794\/revisions"}],"predecessor-version":[{"id":370797,"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=\/wp\/v2\/posts\/370794\/revisions\/370797"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=\/wp\/v2\/media\/370795"}],"wp:attachment":[{"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=370794"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=370794"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zakrasnejsivimperk.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=370794"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}