{"id":364301,"date":"2026-01-01T17:34:47","date_gmt":"2026-01-01T16:34:47","guid":{"rendered":"https:\/\/zakrasnejsivimperk.cz\/?p=364301"},"modified":"2026-01-01T17:34:47","modified_gmt":"2026-01-01T16:34:47","slug":"ceska-republika-tetovani-muze-dlouhodobe-ovlivnovat-imunitni-system","status":"publish","type":"post","link":"https:\/\/zakrasnejsivimperk.cz\/?p=364301","title":{"rendered":"\u010cESK\u00c1 REPUBLIKA: Tetov\u00e1n\u00ed m\u016f\u017ee dlouhodob\u011b ovliv\u0148ovat imunitn\u00ed syst\u00e9m"},"content":{"rendered":"
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Ilustra\u010dn\u00ed foto: pixabay<\/figcaption><\/figure>\n

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V\u011bd\u011bli jste, \u017ee p\u0159i tetov\u00e1n\u00ed nezanech\u00e1v\u00e1te stopu jen na k\u016f\u017ei, ale tak\u00e9 na imunitn\u00edm syst\u00e9mu? Pr\u016flomov\u00e1 mezin\u00e1rodn\u00ed studie, na n\u00ed\u017e se pod\u00edleli i v\u011bdci z\u00a0Biologick\u00e9ho centra Akademie v\u011bd \u010cR, ukazuje, \u017ee b\u011b\u017en\u011b pou\u017e\u00edvan\u00e9 tetovac\u00ed pigmenty maj\u00ed vliv na imunitu, vyvol\u00e1vaj\u00ed z\u00e1n\u011bt a mohou sni\u017eovat \u00fa\u010dinnost n\u011bkter\u00fdch vakc\u00edn.<\/h6>\n

\"\"Hned po aplikaci se barviva rychle \u0161\u00ed\u0159\u00ed lymfatick\u00fdm syst\u00e9mem a hromad\u00ed se v m\u00edzn\u00edch uzlin\u00e1ch, kde p\u0159etrv\u00e1vaj\u00ed cel\u00e9 roky. V\u00fdzkum zkoumal toxicitu t\u0159\u00ed nejpou\u017e\u00edvan\u011bj\u0161\u00edch barev \u2013 \u010dern\u00e9, \u010derven\u00e9 a zelen\u00e9 \u2013 a odhalil, \u017ee pigmenty nejen z\u016fst\u00e1vaj\u00ed v k\u016f\u017ei, ale tak\u00e9 se trvale ukl\u00e1daj\u00ed v imunitn\u00edch bu\u0148k\u00e1ch.<\/p>\n

Do v\u00fdzkumu se zapojilo dvan\u00e1ct mezin\u00e1rodn\u00edch skupin pod veden\u00edm prof. Santiaga F. Gonz\u00e1lese ze \u0161v\u00fdcarsk\u00e9ho Institutu pro v\u00fdzkum v\u00a0biomedic\u00edn\u011b (IRB, Universit\u00e0 della Svizzera italiana). V\u011bdci zjistili, \u017ee inkoust b\u011bhem n\u011bkolika hodin po tetov\u00e1n\u00ed putuje lymfatick\u00fdmi c\u00e9vami a ve velk\u00e9m mno\u017estv\u00ed se hromad\u00ed v lymfatick\u00fdch uzlin\u00e1ch, kde jej aktivn\u011b pohlcuj\u00ed imunitn\u00ed bu\u0148ky – makrof\u00e1gy. Tyto bu\u0148ky, kter\u00e9 b\u011b\u017en\u011b odkl\u00edzej\u00ed cizorod\u00e9 \u010d\u00e1stice jako bakterie, viry \u010di toxiny, v\u0161ak pigment nedok\u00e1\u017eou rozlo\u017eit. To vede k jejich po\u0161kozen\u00ed a bun\u011b\u010dn\u00e9 smrti, nejv\u00fdrazn\u011bji u \u010dern\u00fdch a \u010derven\u00fdch inkoust\u016f.<\/p>\n

Proces tetov\u00e1n\u00ed vyvol\u00e1v\u00e1 z\u00e1n\u011btlivou reakci, kter\u00e1 m\u00e1 dv\u011b jasn\u011b rozpoznateln\u00e9 f\u00e1ze. Nejprve doch\u00e1z\u00ed k akutn\u00edmu z\u00e1n\u011btu, jen\u017e vrchol\u00ed b\u011bhem n\u011bkolika hodin po tetov\u00e1n\u00ed a postupn\u011b odezn\u00edv\u00e1 v pr\u016fb\u011bhu prvn\u00edch dn\u016f. N\u00e1sleduje dlouhodob\u011bj\u0161\u00ed f\u00e1ze, v n\u00ed\u017e z\u00e1n\u011btliv\u00e9 procesy a aktivace imunitn\u00edch bun\u011bk v m\u00edzn\u00edch uzlin\u00e1ch p\u0159etrv\u00e1vaj\u00ed nejm\u00e9n\u011b dva m\u011bs\u00edce. Pigment v\u00a0m\u00edzn\u00edch uzlin\u00e1ch v\u011bdci pozorovali nejen u laboratorn\u00edch my\u0161\u00ed, ale tak\u00e9 v odebran\u00fdch vzorc\u00edch lidsk\u00fdch lymfatick\u00fdch uzlin, a to i mnoho let po tetov\u00e1n\u00ed.<\/p>\n

Studie se v\u011bnovala tak\u00e9 ot\u00e1zce, zda m\u016f\u017ee tetov\u00e1n\u00ed ovlivnit \u00fa\u010dinnost o\u010dkov\u00e1n\u00ed, co\u017e bylo t\u00e9ma, kter\u00e9 z\u00edskalo velkou pozornost b\u011bhem pandemie COVID-19. V\u00fdsledky ukazuj\u00ed, \u017ee tetovan\u00e9 my\u0161i vytv\u00e1\u0159ely po o\u010dkov\u00e1n\u00ed mRNA vakc\u00ednou v\u00fdrazn\u011b m\u00e9n\u011b protil\u00e1tek. D\u016fvodem m\u016f\u017ee b\u00fdt to, \u017ee \u010d\u00e1st imunitn\u00edch bun\u011bk z\u016fst\u00e1v\u00e1 dlouhodob\u011b ovlivn\u011bna pigmentem, h\u016f\u0159e zpracov\u00e1v\u00e1 antigen a poskytuje slab\u0161\u00ed sign\u00e1ly pot\u0159ebn\u00e9 pro tvorbu protil\u00e1tek. Podobn\u011b i lidsk\u00e9 imunitn\u00ed bu\u0148ky vystaven\u00e9 inkoustu reagovaly na antigen m\u00e9n\u011b efektivn\u011b. Tato zji\u0161t\u011bn\u00ed otev\u00edraj\u00ed nov\u00e9 ot\u00e1zky o bezpe\u010dnosti tetov\u00e1n\u00ed i o mo\u017en\u00fdch dopadech u lid\u00ed s rozs\u00e1hl\u00fdmi tetov\u00e1n\u00edmi. \u201eTetovac\u00ed inkoust nen\u00ed z pohledu imunologie neutr\u00e1ln\u00ed. Dok\u00e1\u017ee dlouhodob\u011b m\u011bnit prost\u0159ed\u00ed v lymfatick\u00fdch uzlin\u00e1ch, co\u017e m\u016f\u017ee b\u00fdt d\u016fle\u017eit\u00e9 p\u0159i reakc\u00edch na infekce i p\u0159i o\u010dkov\u00e1n\u00ed,\u201c<\/em> upozor\u0148uje Martin Palus z Biologick\u00e9ho centra Akademie v\u011bd \u010cR.<\/p>\n

V\u00fdzkum touto studi\u00ed zdaleka nekon\u010d\u00ed. V\u011bdci budou d\u00e1le detailn\u011bji zkoumat vztah mezi tetovac\u00edmi pigmenty, imunitn\u00edm syst\u00e9mem a nemocemi. Hlavn\u00ed autor studie Santiago F. Gonz\u00e1lez a Martin Palus ji\u017e spole\u010dn\u011b po\u017e\u00e1dali o grant v programu WEAVE \u2013 Lead Agency, kter\u00fd poskytuje \u0160v\u00fdcarsk\u00e1 n\u00e1rodn\u00ed v\u011bdeck\u00e1 nadace a Grantov\u00e1 agentura \u010cesk\u00e9 republiky. V\u00a0n\u011bm se cht\u011bj\u00ed zam\u011b\u0159it zejm\u00e9na na hlub\u0161\u00ed porozum\u011bn\u00ed tomu, jak tetovac\u00ed barviva ovliv\u0148uj\u00ed imunitn\u00ed odpov\u011b\u010f v kontextu infek\u010dn\u00edch onemocn\u011bn\u00ed.<\/p>\n

Studie, uve\u0159ejn\u011bn\u00e1 v\u00a0presti\u017en\u00edm v\u011bdeck\u00e9m \u010dasopise PNAS<\/strong><\/a>, podtrhuje pot\u0159ebu dal\u0161\u00edho v\u00fdzkumu bezpe\u010dnosti tetovac\u00edch inkoust\u016f i dopad\u016f jejich dlouhodob\u00e9 p\u0159\u00edtomnosti v t\u011ble.<\/p>\n

(tz-av\u010dr)<\/strong><\/p>\n

\n

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